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Monday, 4 April 2022

Bone Marrow Transplant (BMT)

 


Bone Marrow Transplant (BMT) is one of the most advanced treatments from modern medicine. It can be used for treating patients with blood and cancer diseases. In simple terms, BMT is done in two steps. In the first step, the patient is given high dose chemotherapy or radiotherapy or combination to kill the cancer or the diseased marrow (called conditioning) and makes the bone marrow empty. In the second step, the empty marrow is replaced with healthy blood-forming stem cells (called stem cell infusion). This process is known as bone marrow transplants.


Below given are the details of donors in allogeneic BMT.

  • If the donor is 100% HLA matched (usually a sibling), called as Matched Related Donor BMT.
  • If the donor is 100% HLA matched but outside family from a donor registry, called as Matched Unrelated Donor (MUD) BMT.
  • If the donor is 50% HLA matched (usually a family member) then it’s called as Mismatched Related or Haploidentical BMT.

lakh for treatment, he said.Referring to recent cancer registry, Dr Katewa said about 15000 people, including 3000 new born babies, in Rajasthan were reportedly afflicted by leukaemia every year. Bone marrow transplant was the only viable option and her father's 50 per cent stem cell was a high match, Dr Katewa said.Half-matched (haplo-identical) bone marrow stem cell transplant is not very common in India as compared to the west and it was the first 50 per cent matched bone marrow transplant of stem cells donated by the girl's father, he said.The medical procedure was done in June last year, and the girl is hale and hearty now, Dr Katewa said.As against a high cost of Rs. 20 lakh, her parents paid about Rs. In a rare medical procedure, a two- year-old girl suffering from acute blood cancer was given a new lease of life after a successful 50 per cent matched Bone Marrow Transplant (BMT) at a private hospital in Jaipur.Prachi, who hailed from Sikar in Rajasthan, was suffering from acute blood cancer (acute myeloid leukaemia) in June last year, and brought to Manipal Hospital in a critical condition with her eyes nearly protruding out of the sockets, Dr Satyendra Katewa, Head of Paediatric Haemato-Oncology and BMT, told reporters on Wednesday.Chemotherapy was ruled out as chances of her survival were slim, only 15 to 20 per cent. Dr katewa bone marrow case




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